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BRCA Positive Diagnosis

A MyBCTeam Member asked a question 💭
Tampa, FL

Daughter diagnosed as carrying BRCA gene. Mother and grandmother had breast cancer but not BRCA testing. What does this mean. Should sister get testing? Mother?

February 12, 2019
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A MyBCTeam Member

Any immediate female relatives should be tested - sisters, aunts, first cousins - on the fathers side as well as the mutation can come from either parent. It's important to know who is positive for the mutation because risk of cancer is so much higher.

Should be noted that it's tougher in the U.S. because in some states they deny people insurance when they test positive, which stops some women from testing at all. Crazy and sad. Not an issue here in Canada as far as I know

February 13, 2019
A MyBCTeam Member

I would inform them and let them decide what to do

February 12, 2019
A MyBCTeam Member

I also went to a genetic counselor and she said that the family pattern is just as important as a genetic test. But also my doctor said that she had a few patients who were well into their 70's that have the BRCA mutation..its not a for sure --you just never know what triggers these cancer cells.

February 12, 2019
A MyBCTeam Member

yes I think everyone-cousins too. I have a genetic mutation (ATM gene) and I informed all my cousins. Some did the testing some did not. People have different philosophies and that's ok-but anyone in my family I let them know so they can get better testing and more aggressive testing of breast and colon. Helps if insurance company knows all the information so they don't hold up any process.

February 12, 2019
A MyBCTeam Member

A BRCA-positive diagnosis indicates that you have an inherited BRCA gene mutation, which increases your risk of developing breast cancer and possibly other types of cancer. Here are some key points:

- Increased Risk: Women with a BRCA mutation have a 50-70% chance of developing breast cancer in their lifetime, compared to Show Full Answer

A BRCA-positive diagnosis indicates that you have an inherited BRCA gene mutation, which increases your risk of developing breast cancer and possibly other types of cancer. Here are some key points:

- Increased Risk: Women with a BRCA mutation have a 50-70% chance of developing breast cancer in their lifetime, compared to 13% in the general population.
- Preventive Measures: If you haven't developed cancer, preventive treatments and earlier, more frequent screenings can help lower your risk.
- Family Testing: Family members may also want to be tested to see if they carry the mutation.
- Treatment Options: If diagnosed with breast cancer, BRCA-positive cancers can be treated with PARP inhibitors like olaparib (Lynparza) and talazoparib (Talzenna).

For more detailed information, you can refer to the resources provided in your knowledge base.

July 15, 2024

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