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I’m Trying To Compare Herceptin + Perjeta Versus Kadcyla. Any Experiences To Share With Kadcyla?

A MyBCTeam Member asked a question 💭
Fort Myers, FL

I’m trying to assess benefits versus costs of each treatment. Side effects versus survival...

February 27, 2019
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A MyBCTeam Member

Hi JanieH, I was on H/P and tolerated well. After surgery pathology indicated small amount of residual cancer in tumor, my onc recommended Kadcyla. She said it is a better option for me than H/P. Her concern is the potential side effect of neuropathy in extremities. (Especially concerning since I have lingering neuropathy from my chemo treatments). She says if it starts to get worse, we will switch back to H/P. I've had 3 of 14 treatments. So far, neuropathy is not better but also not worse. Next treatment is July 19 and plan is to also start Anastrozole at that time.
Wishing you the best
Fiesty

July 3, 2022
A MyBCTeam Member

I didn’t think you could get Kadcyla without having Herceptin first. Everything I have read about doesn’t seem great and the statistics aren’t good enough for me to want to try it. The side effects seem worse than Herceptin as well but Herceptin and Perjeta were really easy for me. I didn’t have any issues and I don’t doubt it saved my life.

March 2, 2019
A MyBCTeam Member

Certainly! Here is some detailed information about Kadcyla (Ado- Trastuzumab Emtansine) based on the knowledge base:

Kadcyla (Ado- Trastuzumab Emtansine) for Breast Cancer

Overview
- Type: Biologic drug, specifically an antibody-drug conjugate.
- Target: HER2-positive breast cancer cells.
- Mechanism: Combines an Show Full Answer

Certainly! Here is some detailed information about Kadcyla (Ado- Trastuzumab Emtansine) based on the knowledge base:

Kadcyla (Ado- Trastuzumab Emtansine) for Breast Cancer

Overview:
- Type: Biologic drug, specifically an antibody-drug conjugate.
- Target: HER2-positive breast cancer cells.
- Mechanism: Combines an antibody targeting HER2-positive cells with a drug that kills these cells.

Usage:
- Administration: Intravenous injection once every three weeks.
- Form: Single-use vials.
- Indications:
- Used in cases where trastuzumab and a taxane drug have already been used.
- Prescribed if breast cancer recurs within six months of adjuvant (post-surgery) treatment.

Side Effects:
- Common:
- Fatigue
- Nausea
- Musculoskeletal pain
- Thrombocytopenia (decrease in platelets)
- Headache
- Increased liver enzymes
- Constipation
- Nosebleeds
- Rare but Serious:
- Heart problems
- Lung issues
- Liver complications
- Immune system problems
- Blood clotting issues
- Nerve damage (numbness, tingling, or pain in hands and feet)

Effectiveness:
- Action: Targets and kills breast cancer cells, slowing tumor growth.

For more detailed experiences and information, you can visit the [Kadcyla page on MyBCTeam](https://www.mybcteam.com/treatments/kadcyla).

If you have any specific questions or need further details, feel free to ask!

July 30, 2024
A MyBCTeam Member

Congrats on completing treatment. You go!

March 3, 2019
A MyBCTeam Member

@A MyBCTeam Member January 18, 2018 was my last Herceptin/Perjeta. I was stage 1 Grade 3 no lymph node involvement. I found my lump in between mammograms.

March 2, 2019

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