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I Am 3 Year From Diagnosis. TNBC / BRCA2 Double Mastectomy (complete Response)/bilateral Oopherectomy. Want To Consider HRT. Am I Crazy?

A MyBCTeam Member asked a question 💭

IDC TNBC/ BRCA2
Mastectomies 9/2021
Oopherectomy 12/2021
Very seriously considering HRT due to the dramatic aging that I’ve experienced as well as protective benefits with regards to cognitive function, cardiovascular health, bone density / osteoporosis, skin issues. My Doc is on board, but she expressed that there is a risk of secondary cancer and of course that scares the crap out of me…. But honestly it’s also a huge quality of life issue too.

August 23, 2024
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A MyBCTeam Member

Considering hormone replacement therapy (HRT) after a diagnosis of triple-negative breast cancer (TNBC) and BRCA2 mutation, especially after a mastectomy and bilateral oophorectomy, is a complex decision. Here are some key points from your knowledge base:

- Risk Factors: If you've had a diagnosis of breast cancer or tested Show Full Answer

Considering hormone replacement therapy (HRT) after a diagnosis of triple-negative breast cancer (TNBC) and BRCA2 mutation, especially after a mastectomy and bilateral oophorectomy, is a complex decision. Here are some key points from your knowledge base:

- Risk Factors: If you've had a diagnosis of breast cancer or tested positive for a breast cancer gene (like BRCA2), your doctor will likely not prescribe HRT due to increased risks.
- HRT and Breast Cancer: Combined HRT (estrogen and progestin) is associated with a higher risk of breast cancer, particularly estrogen-receptor-positive and HER2-positive cancers.
- Alternatives: There are non-hormonal ways to manage menopausal symptoms, such as:
- Limiting caffeine and alcohol
- Practicing relaxation techniques
- Maintaining a healthy weight and exercising
- Considering non-hormonal medications or local hormone therapies (like creams)

It's crucial to discuss your specific situation with your doctor to weigh the pros and cons and explore safer alternatives.

August 23, 2024

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