In the beginning of my diagnosis I was put on letrozole. My side-effects were minimal in the beginning, very tolerable as far as bone pain goes. I had more hot flashes and night sweats, headaches. The bone pain started about 6months in. Then progressed. The drop in estrogen causes the pain. I was feeling the accumulative effects of the blocker. The longer I took it, the more I hurt. At month 19 I was miserable, but I tolerated it. These blockers effect each one different. Your experience may be entirely different from mine. I have less pain with the Faslodex shots. Letrozole quit working for me and my tumor markers started going up. The shots brought my markers back down ,thank goodness! Talk to your doctor about your pain. If they don't know what's going on they can't help! 🙂👍

I used 3 different blockers with horrendous side effects while using each one. Then 4 years in, the DCIS returned in the same breast and I had to have a BMX. So essentially I went through that horror for no reason.

Hi, yes I have been changing meds so often because of the pain. You are correct it affects you after you have been on it for a while.

I am so sorry Linda . That is terrible. And I don't want to go through years of pain just to die anyway. At stage 4 I was told I would have to take them for the rest of my life so that means if I was to live another 10 years, it would be 10 years of pain. Do I want that? Hell no.

Whats a woman supposed to do with these hormone blocking meds when all 3 basically have the same effects, bone/joint pain? Because they block estrogen and this is the result.