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Do Aromatase Inhibitors Raise Retinal Adverse Event Risk?

A MyBCTeam Member asked a question 💭
Rochester, NY

Ophthalmology Advisor.

Three aromatase inhibitors (AIs) commonly used to treat hormone receptive-positive breast cancer elevate a patient’s risk for ocular adverse events (AEs), according to research published in the Canadian Journal of Ophthalmology. Jan.2024

The study shows increased incidences of ocular dysfunctions such as vitreoretinal disorders and uveitis, say a research team who queried the US Food and Drug Administration’s Adverse Events Reporting System (FAERS).

Their data search… read more

June 23, 2024
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A MyBCTeam Member

I have actually just found it easier to increase all of my physician visits. I see my GP monthly and have eye exams yearly. I have found ways to get insurance to cover it with all my health conditions and issues. I save the citation information for studies that apply to my conditions in case I have issues with coverage. I know the side effects can be awful. I pursue relief for the ones that bother me but I do everything I can to prevent the other possible ones and then just move on. Worrying about it doesn't help anything. If it happens I am prepared and will deal with it then.

June 23, 2024
A MyBCTeam Member

It seems each AI has negative side effects that impact individuals more or less intensely. I have tried five versions over a period of three years and suffered debilitating conditions. I felt as if the “cure” was worse than the risk of recurring disease, and am currently OFF estrogen blockers. Outside of normal age related wear and tear I am feeling so much healthier in general.

My body doesn’t tolerate a number of prescribed medications. With AI’s doctors prescribe high dosages to each patient first, when perhaps a lower amount would prove to be as effective without such harsh side effects. Why? I found there are few to zero studies for lower dosage effectiveness, so who benefits most from the current high dose approach? Is it really the patient outcomes or the profits that run this machine called treatment?

June 24, 2024
A MyBCTeam Member

It is really concerning to me that there are so many dangers t some of the meds they want us t take to our kidneys, liver and eyes now too. I am 80 years old and some of blood labs are up. I am going to have some serious talk with my oncologist about this.

June 23, 2024
A MyBCTeam Member

They tell you the onocolgist if you have vision problems to contact them. Again why aren't we told about these other problems before hand. Plus we might also get cataracts just great.

June 23, 2024
A MyBCTeam Member

Oh lord, when does it stop... The gift that keeps giving is a under statement, to say the least. Def so on estrogen. If we didnt need it our bodies wouldn't make it. My cousin takes the letrozole 3 times a week. Like Sue said it accumulates it, so maybe 3 times a week is enough?

June 23, 2024

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